(5) glucose dysregulation suppresses the expression of antioxidant genes via the Nrf2/ARE pathway, weakening the antioxidant defense and DNA repair capacity of the p53 pathway (48, 49)
The safety profile is primarily derived from case series, observational studies, and clinical experience from private practitioners rather than formal pharmacovigilance systems
NF-kB plays a central role in controlling immune responses, but its overactivation in IC leads to increased expression of inflammatory mediators and a reduction in normal cell turnover
Our data have revealed that MZB and FoB rely on activities that differ in their dependence on GSH
CrossRef Combination of Berberine and Evodiamine Alleviates Obesity by Promoting Browning in 3T3-L1 Cells and High-Fat Diet-Induced Mice Huiying Zhang, Peiyu Xiong, Tianyan Zheng, Youfan Hu, Pengmei Guo, Tao Shen, Xin Zhou International Journal of Molecular Sciences.2025